{"id":2297,"date":"2016-09-09T15:41:22","date_gmt":"2016-09-09T19:41:22","guid":{"rendered":"http:\/\/www.imperialcrs.com\/blog\/?p=2297"},"modified":"2025-07-07T18:21:04","modified_gmt":"2025-07-07T18:21:04","slug":"getting-patient-recruitment-right-from-the-start-planning-your-protocol","status":"publish","type":"post","link":"https:\/\/www.imperialcrs.com\/blog\/patient-recruitment-and-retention\/getting-patient-recruitment-right-from-the-start-planning-your-protocol\/","title":{"rendered":"Getting Patient Recruitment Right from the Start: Planning Your Protocol"},"content":{"rendered":"<p style=\"text-align: left;\"><span style=\"color: #000000;\"><strong>This is the first of two posts containing\u00a0excerpts from our forthcoming ebook on proactive recruitment planning.\u00a0<\/strong><\/span><\/p>\n<p style=\"text-align: left;\"><a href=\"https:\/\/www.centerwatch.com\/\">CenterWatch<\/a> data tells us that in clinical trials, too many patients who volunteer don\u2019t qualify, or they leave the study after they are enrolled.<\/p>\n<p>69% fail prescreening<\/p>\n<p>58% decline consent<\/p>\n<p>32% fail screening<\/p>\n<p>18% drop out after enrollment<\/p>\n<p>Why are these metrics meaningful? Too often, the protocol comes first, then patient considerations come later. These statistics could improve greatly through proactive protocol planning.<\/p>\n<p>When planning your protocol, ask yourself:<\/p>\n<ul>\n<li>Am I looking at the study from the patient\u2019s perspective?<\/li>\n<li>Does my protocol take into consideration whether these patients really exist?<\/li>\n<li>Are the obligations put on the patient fair?<\/li>\n<\/ul>\n<p>The graphic below, also from CenterWatch data, presents additional considerations to take in account during the protocol design process as well as communication with the patient:<\/p>\n<p><a href=\"https:\/\/www.imperialcrs.com\/blog\/wp-content\/uploads\/2016\/09\/Failed-Trial_1b-003.jpg\" data-rel=\"penci-gallery-image-content\" ><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2334\" src=\"https:\/\/www.imperialcrs.com\/blog\/wp-content\/uploads\/2016\/09\/Failed-Trial_1b-003-960x747.jpg\" alt=\"Failed Trial_1b (003)\" width=\"960\" height=\"747\" \/><\/a><\/p>\n<p>By addressing these specific issues early on, it will be easier to establish realistic expectations on patients before they join the study, and it will limit them as reasons for attrition.<\/p>\n<p>Protocol crowdsourcing is growing in popularity. This, along with other new market research methods and focus group surveys, are bringing protocols to the patient early to get a patient perspective on protocol components. This is useful information.<\/p>\n<p>It is also vital to consider the caregiver requirements if they will be helping a patient participating in the study. With the increase in the number of Alzheimer\u2019s and oncology studies, more caregivers are playing a critical role in the retention and compliance of patients.<\/p>\n<p>This is an open opportunity for our industry. When prospective patients (and caregivers when applicable) are able to provide feedback around items such as informed consent, site visit requirements, and procedures, this information can be applied to make proactive adjustments to protocols. This collaboration will lower the rates of attrition &#8212; dollars will be saved and more studies will finish on time.<\/p>\n<p><em>next week<\/em>: \u00a0my colleague Melynda Geurts discusses where prospective patients get their information<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This is the first of two posts containing\u00a0excerpts from our forthcoming ebook on proactive recruitment planning.\u00a0 CenterWatch data tells us that in clinical trials, too many patients who volunteer don\u2019t qualify, or they leave the study after they are enrolled. 69% fail prescreening 58% decline&hellip;<\/p>\n","protected":false},"author":7,"featured_media":71598,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[35],"tags":[208,1722,1719,1231,1721,1720,34,73,1718,165,1717,1666],"class_list":["post-2297","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-patient-recruitment-and-retention","tag-clinical-trial-recruitment","tag-enhancing-recruitment-success","tag-enrollment-planning","tag-informed-consent-process","tag-optimizing-trial-design","tag-participant-engagement","tag-patient-recruitment","tag-patient-recruitment-planning","tag-patient-centric-protocols","tag-protocol-design","tag-protocol-design-strategies","tag-recruitment-strategies"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Plan Your Protocol to get Patient Recruitment Right<\/title>\n<meta name=\"description\" content=\"Is it in a patient\u2019s perspective? 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