{"id":1442,"date":"2015-11-24T02:27:35","date_gmt":"2015-11-24T02:27:35","guid":{"rendered":"http:\/\/www.imperialcrs.com\/blog\/?p=1442"},"modified":"2022-02-07T19:00:25","modified_gmt":"2022-02-07T19:00:25","slug":"7-reasons-for-patient-enrollment-challenges","status":"publish","type":"post","link":"https:\/\/www.imperialcrs.com\/blog\/patient-recruitment-and-retention\/7-reasons-for-patient-enrollment-challenges\/","title":{"rendered":"7 Reasons for Patient Enrollment Challenges"},"content":{"rendered":"

In my last post I covered facts on enrollment delays from my latest ebook. \u00a0In this post I’m going to cover\u00a0the seven most common reasons for these enrollment challenges.<\/p>\n

There are a number of reasons that sites may struggle or fail to enroll patients – we could\u00a0write an entire novel on them! Here are the most common:<\/p>\n

Protocol Criteria
\n<\/strong>Some professionals will argue that the industry is too restrictive in\u00a0protocol requirements. This may be true in some instances, but there are reasons for being\u00a0stringent as well, especially in earlier phase trials.<\/p>\n

Identifying Patients
\n<\/strong>There are many factors that can make patient identification a\u00a0challenge; patient demographics, location, and indication are all factors that can cause\u00a0hurdles for sites.<\/p>\n

Screen Failures
\n<\/strong>Sites often receive a protocol and think that a much higher number\u00a0of patients coming through their practice would qualify. Often when these patients are\u00a0actually brought in for screening, they don\u2019t qualify for any number of reasons.<\/p>\n

Consent
\n<\/strong>Consent can be a large hurdle when working with children or trials in the early\u00a0stages.<\/p>\n

Competing Sites
\n<\/strong>Currently there are more clinical trials operating than ever before.\u00a0Competing studies may certainly be tapping into your patient pool.<\/p>\n

Site Fatigue
\n<\/strong>Site fatigue is often overlooked. The longer a trial goes on, the harder it is to\u00a0keep the attention and enthusiasm of the sites and their teams. Once sites lose motivation,\u00a0it is often tough to revive it.<\/p>\n

Fairness of Grant
\n<\/strong>If investigators are not paid as well as they are for other studies, yours\u00a0may not receive the attention it needs. The grant needs to be competitive.<\/p>\n

Typically, the strongest factors hindering enrollment are screen failures and the inability\u00a0to identify enough qualified patients, followed not too far behind by excessive protocol\u00a0criteria.\u00a0These three factors should be on top of the mind throughout the planning stages\u00a0in order to prepare sites proactively.<\/p>\n

These are the most common patient enrollment challenges faced by the industry. \u00a0For more information on how to turn around a trial with low patient enrollment, be sure to\u00a0download my ebook here.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

In my last post I covered facts on enrollment delays from my latest ebook. \u00a0In this post I’m going to cover\u00a0the seven most common reasons for these enrollment challenges. 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